What is Nabota?
Nabota is a Botulinum Toxin Type A product from Daewoong Pharmaceutical, South Korea.
The medicine helps reduce signals from nerves to muscles, temporarily reducing activity in the muscles injected.
For wrinkles, muscles that repeatedly fold the skin move less, so expression lines look softer.
For the jaw muscles, Masseter activity decreases and muscle size may gradually decrease over time.
What is HI-PURE Technology?
Daewoong states that Nabota is manufactured using HI-PURE™ Technology.
This technology is part of Botulinum Toxin manufacturing and purification. The manufacturer holds patents for it in both South Korea and the United States.
For people receiving injections, also check that the product is genuine, its origin is verifiable, and the amount suits their own muscles.
Is Nabota approved by the US FDA?
The prabotulinumtoxinA product manufactured by Daewoong received US FDA approval in 2019 under the brand name Jeuveau®.
In the US, Jeuveau is approved to temporarily improve the appearance of moderate to severe frown lines in adults.
The US FDA lists Nabota and Jeuveau as names associated with prabotulinumtoxinA.
Indications and brand names may differ by country. For use in Thailand, follow the product’s Thai registration information.
Nabota highlights
- Uses HI-PURE™ technology , a patented purification process developed by Daewoong
- Purity greater than 98%
- Produced from Botulinum Toxin Type A, Hall strain
- Manufactured by Daewoong Pharmaceutical, South Korea , with a dedicated Nabota manufacturing facility
- Registered in many countries worldwide ; Daewoong states that it is currently approved in more than 60 countries
- The same substance has US FDA approval under the Jeuveau® name
Where can Nabota be used?
Expression lines
Botulinum Toxin suits lines caused by repeated muscle movement, such as:
- Forehead lines
- Frown lines
- Crow's feet
As muscles in the area move less, lines appearing when raising the eyebrows, frowning or smiling look softer.
Masseter muscles
For people whose broad jaw area is caused by the Masseter muscle.
After injection, muscle activity gradually decreases. Over time muscle size may decrease, making the lower face look slimmer within the original facial structure.
If jaw width comes mainly from bone or fat, botulinum toxin cannot directly reduce those components.
Jawline
Botulinum Toxin can be planned for certain muscles around the jawline and neck.
The goal is to reduce the force of certain muscles pulling the jawline down, making the jaw contour look more refined.
This does not lift skin like a skin-firming device or dissolve fat under the chin.
Who might Nabota suit?
It may suit people who:
- Have wrinkles when moving the face
- Have forehead lines
- Have frown lines
- Have crow’s feet
- Have relatively large masseter muscles
- Want the jaw area to look slimmer
- Want to refine the facial contour
- Have had Botulinum Toxin before and are choosing a product for the next treatment
If you have been injected elsewhere, tell the doctor the brand, unit count and date of your latest injection if you remember.
How many units of Nabota are used?
There is no single number suitable for everyone.
Wrinkles, forehead, crow’s feet and masseter muscles require different unit counts. Even at the same site, people with strong muscles and people with small muscles may need different amounts.
The doctor considers:
- Intended injection sites
- Muscle size
- Muscle strength
- Facial movement
- Desired results
- Previous injection history
The unit count should reflect the actual muscles rather than choosing the promotion offering the most units.
Do all 100 Units of Nabota need to be used?
No.
100 Units is the amount in one vial, not an instruction for everyone to receive all 100 units.
Wrinkle injections may use only part of a vial, while areas with larger muscles, such as the masseter, may require more.
The actual amount requires an assessment of the site and muscle strength first.
How many days until Nabota results appear?
Botulinum Toxin does not produce results immediately after injection.
Results may begin to appear from around 2 days, becoming gradually clearer afterward.
The masseter takes longer: besides waiting for the medicine to reduce muscle activity, muscle size also needs time to gradually change.
Do not rush to judge results from the first few days after injection.
How long does Nabota last?
The effects of Botulinum Toxin are temporary.
Over time, the muscles gradually start working again.
Duration varies according to:
- Injection area
- Unit count
- Muscle strength
- Daily muscle use
- Individual response
When you start to feel the muscles moving more again, return for the doctor to check before repeat injections.
Will my face look frozen after Nabota?
Not necessarily.
A face that feels too still or unable to move enough relates to the injection sites and amount, not the brand alone.
For a natural look, tell the doctor before treatment that you want fewer wrinkles while still being able to raise your eyebrows, smile and show expressions.
An amount appropriate for the muscles matters more than using many units.
How does Nabota differ from other Korean botulinum toxin brands?
Each brand has its own manufacturer, production process, formulation and study data.
For Nabota, information specific to the product includes:
- Manufactured by Daewoong Pharmaceutical
- Uses HI-PURE™ Technology according to the manufacturer
- Nabota has Thai FDA registration
- Daewoong-manufactured prabotulinumtoxinA is approved in the US under the Jeuveau® name
This does not mean one brand is always more suitable than another for everyone.
For injections, consider the product, intended treatment sites, amount and muscle strength together.
How can I identify genuine Nabota?
Before injection, you should be able to inspect the product being used.
Things you can inspect include:
- Nabota name on the product
- Box and vial in good condition
- Lot number
- Expiry date
- Manufacturer information
- Thai FDA registration number
- Matching information on the box and vial
For further reassurance, check the product name and registration number in the Thai FDA database.
Check the product before injection at The Ality
Before use, you can see the product to be injected, including its box, vial, lot number and related information.
The box is opened for you to see, and you can check the product before actual use.
Besides choosing how many units you want, you should know which medicine is used, where it comes from and whether it can be verified.
Nabota injection steps
1. Assess the concern to address
First, check whether the concern is wrinkles, masseter muscles or another area.
2. Assess the muscles
The doctor may ask you to raise your eyebrows, frown, smile or clench your teeth to assess actual muscle strength.
3. Plan sites and unit count
Choose sites and amount according to the muscles.
4. Check the product
Check the box, vial and product information before use.
5. Inject
The procedure does not take long.
6. Aftercare
After treatment, you can return to normal daily activities while following the doctor’s advice.
What should I tell the doctor before injection?
Tell the doctor if you have:
- Underlying conditions
- A history of drug allergies
- Current medications or supplements
- Previous Botulinum Toxin injections
- Previous brands and injection dates, if known
- Previous abnormal symptoms after injection
- Neurological or muscle disorders
- Pregnancy or breastfeeding
- Inflammation or infection at the planned injection site
Aftercare
After treatment, you should:
- Do not press or massage the newly injected area yourself
- Keep needle punctures clean
- Avoid impacts to the treated area
- Monitor symptoms after injection
- Wait for the medicine to take effect before assessing results
- Return for follow-up as advised by the doctor
Nabota information
- Product name: Nabota®
- Active substance: Botulinum Toxin Type A
- Manufacturer: Daewoong Pharmaceutical Co., Ltd.
- Country of manufacture: South Korea
- Size registered in Thailand: 100 Units / Vial
- Thai FDA registration number: 1C 3/57(BF)
- Form: Powder for preparing a solution before injection
The manufacturer offers several Nabota sizes overseas, but the Nabota product verifiable in Thailand’s drug register is 100 Units per vial.