What is Hutox?
Hutox is a Botulinum Toxin Type A product from Huons BioPharma, South Korea.
The medicine reduces signalling between nerves and muscles, temporarily reducing muscle activity at injection sites.
For wrinkles, lines appearing when frowning, raising the eyebrows or smiling look softer as muscle movement decreases.
Use in larger muscles requires case-by-case review of the location and indications, with the doctor planning treatment to suit each person.
Which strain does Hutox use?
Hutox uses Botulinum Toxin Type A originating from the ATCC3502 strain.
This strain is part of the manufacturing information for Huons BioPharma’s Hutox product.
Actual injection results depend on more than the strain: injection sites, unit count and each person’s muscle characteristics also matter.
Hutox highlights
- Botulinum Toxin Type A from South Korea
- Manufactured by Huons BioPharma
- A 100 Units product is registered with the Thai FDA
- The manufacturer specifically develops and manufactures Botulinum Toxin
- The manufacturer states that its manufacturing process achieves high purity
- Units can be adjusted to location and muscle strength
- Injections take little time
- Generally does not require prolonged recovery
Where can Hutox be used?
Frown lines
This is one of the areas with direct Hutox study data.
Frown lines result from repeated activity of muscles between the eyebrows. As these muscles move less, lines appearing when frowning look softer too.
Crow's feet
Huons BioPharma also lists Hutox use for lines around the eyes in some countries.
These lines arise from activity of muscles around the eyes when smiling, laughing or squinting.
When muscle activity decreases, lines appearing while smiling can look softer.
Expression lines
Botulinum Toxin works on muscles, so it suits wrinkles from repeated facial movement more than lines caused by skin hollowing or facial structure.
Before treatment, the doctor asks you to move your face to identify which muscles actually cause the lines.
Masseter muscles
Botulinum Toxin can reduce activity of the Masseter muscle.
For masseter treatment, the doctor must first check whether jaw width really comes from muscle, then plan according to indications and individual suitability.
If jaw width comes from bone or fat, botulinum toxin does not directly reduce those components.
Jawline
The doctor may plan Botulinum Toxin use in certain muscles around the jawline and neck.
The goal is to reduce the force of certain muscles, not to pull skin up or dissolve fat under the chin.
Who might Hutox suit?
It may suit people who:
- Have expression lines
- Have noticeable frown lines
- Have lines around the eyes when smiling
- Want to reduce activity in certain muscles
- Have had Botulinum Toxin before and are choosing a product for the next treatment
If injected elsewhere, tell the doctor the brand, unit count and latest injection date if you remember, so they can check whether any previous effect remains.
How many units of Hutox are used?
There is no single number suitable for everyone.
Even at the same site, people with strong muscles and people with small muscles may need different amounts.
The doctor considers:
- Intended injection sites
- Muscle strength
- Muscle size
- Facial movement
- Whether you have had injections before
- How much muscle movement you want to retain
Unit count should reflect the actual muscles, rather than choosing the promotion offering the largest amount.
How many days until Hutox results appear?
Botulinum Toxin does not produce results immediately after injection.
Hutox product information states that changes may generally begin around 3–7 days after injection and gradually become clearer at around 1–2 weeks.
For a larger muscle such as the masseter, facial-shape changes take longer than wrinkle changes because muscle size also needs time to gradually change.
How long does Hutox last?
The effects of Botulinum Toxin are temporary.
Product information gives a possible duration of around 3–6 months, with actual duration differing by person.
Factors include:
- Injection sites
- Unit count
- Muscle strength
- Daily muscle use
- Individual response
When muscles begin moving more again, return for the doctor to check before repeat injections.
Will my face look frozen after Hutox?
Not necessarily.
Feeling that the face is too still or frozen relates more to injection sites and amount than to the brand name alone.
For a natural look, tell the doctor before injection, for example:
- Want fewer lines but still be able to move
- Still want to raise your eyebrows
- Want your smile to still look like you
- Do not want the forehead to be too immobile
Using an appropriate amount matters more than injecting as much as possible.
How does Hutox differ from other botulinum toxin brands?
Each Botulinum Toxin brand has its own manufacturer, production process, formulation and method of measuring potency units.
For Hutox, information specific to the product includes:
- Manufactured by Huons BioPharma
- Made in South Korea
- Botulinum Toxin Type A
- ATCC3502 strain information
- A 100 Units product registered in Thailand
- The manufacturer has study data on frown lines and additional aesthetic indications in some countries
This does not mean Hutox is always more suitable than other brands for everyone.
When choosing, consider the product, intended injection sites, amount and muscle strength together.
How can I identify genuine Hutox?
Before injection, you should be able to check the actual product being used.
Things to check include:
- The HUTOX INJ.
- States 100 Units
- Box and vial in good condition
- Lot number
- Expiry date
- Manufacturer information: Huons BioPharma
- Thai FDA registration number
- Matching information on the box and vial
Thai packaging may differ from Hutox box images seen overseas, so use Thai registration information and packaging as the main checks.
Check the product before injection at The Ality
Before use, you can see the box, vial, lot number and product information.
Opened for you to see before use, verifiable, and never secretly switched for another product.
Choosing botulinum toxin should not stop at “how many units.” You should also know what medicine is used and whether its origin can be verified.
Hutox injection steps
1. Assess the area you want to address
First, check whether the concern is wrinkles or muscles in a particular area.
2. Assess the actual muscles
The doctor may ask you to frown, raise your eyebrows, smile or move the muscles at the planned treatment site.
3. Plan sites and unit count
Choose sites matching the muscles and desired result.
4. Check the product
Check the box, vial, lot and information before use.
5. Inject
The procedure does not take long.
6. Aftercare
After treatment, you can return to normal daily activities while following the doctor’s advice.
What should I tell the doctor before injection?
Tell the doctor if you have:
- Underlying conditions
- A history of drug allergies
- Current medications or supplements
- Previous Botulinum Toxin injections
- Previous brands and injection dates, if known
- Previous abnormal symptoms after injection
- Neurological or muscle disorders
- Pregnancy or breastfeeding
- Inflammation or infection at the planned injection site
Aftercare
After treatment, you should:
- Do not press or massage the newly injected area yourself
- Keep needle punctures clean
- Avoid impacts to the treated area
- Monitor symptoms after injection
- Wait for the medicine to take effect before assessing results
- Return for follow-up as advised by the doctor
Hutox information
- Product name: HUTOX® INJ.
- Active substance: Botulinum Toxin Type A
- Manufacturer: Huons BioPharma Co., Ltd.
- Country of manufacture: Republic of Korea
- Size registered in Thailand: 100 Units / Vial
- Thai FDA registration number: 1C 8/66(NB)
- Form: Freeze-dried powder for preparing a solution before injection
Hutox 100 Units has been approved for registration in Thailand since 2023.

